What is Erythema Multiforme?

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What are the oral lesions associated with Erythema Multiforme ?

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EM aetiology is unknown but it is thought to be a hypersensitivity reaction triggered by multiple factors. Some of these include reactions to drugs and viral infections, often HSV(found in 70% of cases).

It causes skin lesions that have a distinct appearance known as target lesions. It affects women more than men.  EM affects the oral mucosa causing

  • Desquamative gingivitis
  • Ulcerative lesions on the cheeks and lips
  • In some forms, the lesions may have a thick crusty layer

Further info and images here on a JCDA EM case study.

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